South America Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to CA $1,096 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top vacation destinations in South America
Sao Paulo
Top South America Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Jazz Apartments
Zona T
per person
Oct 23 - Oct 27
found 14 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Bogotá (BOG)
9/10 Wonderful! (300 reviews)
During my stay, the hotel was understaffed, particularly at breakfast. Nevertheless, the staff was very attentive and eager to assist.
Reviewed on Aug. 6, 2025
Petit Palace Apart Hotel Suites
Miraflores
per person
Sep 23 - Oct 3
found 1 day ago
Roundtrip flight included
Edmonton (YEG) to Lima (LIM)
8.6/10 Excellent! (436 reviews)
Comfortable. Excellent location.
The massage chairs in the lobby are a HUGE Plus!! we really enjoyed them after walking all day around the city.
The breakfast could be served earlier (available only from 7:30-10:30am). And it would be nice if they had a cafeteria instead of bringing it to the room as it felt a little cramped for us to eat in the guest room.
Reviewed on Aug. 3, 2025
South America Hotel Deals
Rochester Classic
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is CA $104 per night from Aug 13 to Aug 14
CA $104
CA $109 total
Aug 13 - Aug 14
7.8/10 Good! (404 reviews)
"Excellent location in downtown with best value and services. 10 minutes walk to shopping, theaters, restaurants, subway, and 1 block from main retail street (Av. Corrientes = 42nd St in NYC) for taking taxi."
Reviewed on Mar. 12, 2023
Regal Pacific Buenos Aires
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Aug 14 to Aug 15
CA $145
CA $150 total
Aug 14 - Aug 15
8.8/10 Excellent! (1,000 reviews)
"Very nice hotel and reasonably priced. Staff is quite friendly and responsive. Will stay there again."
Reviewed on May 12, 2025
Concorde Hotel
25 De Mayo 630, Buenos Aires, Capital Federal
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."
Reviewed on Mar. 6, 2018
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in South America
Antonio Pires de Campos Park
Explore the great outdoors at Antonio Pires de Campos Park, a lovely green space in Cuiabá. Stroll along the riverfront or experience the area's museums.
Our Lady of Bom Despacho Church
You can learn about the history of Cuiabá when you stop by Our Lady of Bom Despacho Church. Discover the area's museums and cathedral.
Eurico Gaspar Dutra Stadium
Catch an event at Eurico Gaspar Dutra Stadium during your trip to Cuiabá. Amble around the area's riverfront or visit its cathedral.
Other vacations you might like
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
Expedia's Latest Trends
Hotels
- All Inclusive Resorts and Hotels in Colombia
- All Inclusive Resorts and Hotels in Rio de Janeiro State
- All Inclusive Resorts and Hotels in Argentina
- All Inclusive Resorts and Hotels in Ecuador
- All Inclusive Resorts and Hotels in Chile
- All Inclusive Resorts and Hotels in Guyana
- All Inclusive Resorts and Hotels in Peru
- Beach Hotel in Guyana
- All Inclusive Resorts and Hotels in Brazil
- All Inclusive Resorts and Hotels in Uruguay
Flights
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.